Regularly use it.

Very effective 

Love these patches. I would usually put these on my problem spots right before bed. When I wake up in the morning and remove the patches, the swelling of the spot would be less. The only this is to make sure the skin around the area you're putting this on is not oily. I had waken up so many times to see a patch missing form my face, only to find it on my bed or my hair. Besides that I love these patches, I keep buying them.

I bought this one for my little brother who is concern about acne at age 13.

leave this on overnight , the next morning your pimple will be so much flatter and
less red

The acne patch heals my pimple heal faster.